One of Slimesito's earliest releases was the 2016 single "Yo No Se". The track was released on June 2, 2016 on the artist's SoundCloud account. The track quickly gained traction among local Clayon County aka residents and some of his friends.
After gaining local buzz, he teamed up with Lil Yachty's brother K$upreme for the single "Sleep At Night". After gaining more popularity, he collaborated with fellow Atlanta Producer Mexikodro on the song "Kick That Door" on his joint EP with artist "BeezyB".